ACCQPrep SFC

Teledyne Isco

ACCQPrep SFC

Green Preparative SFC: Chiral or Achiral Separations in a single, compact solution

Information

The ACCQPrep® SFC is a compact system that simplifies method complexity and ensures successful separations for users of all experience levels. As the only system to enable both bulk collection from stacked injections, and multi-sample, open-access with an optional SFC AutoSampler (2×2 or 4×2), the ACCQPrep SFC offers versatility without limitations; all in the smallest Prep SFC footprint on the market.

Comprehensive Chromatography

Chiral or achiral purifications. Excellent orthogonal technique to reversed-phase HPLC
Alternative selectivity from many stationary phase options and a wide solvent polarity range

Green Chromatography

Greatly reduces solvent consumption.
Reducing solvent waste generated and energy needed to remove solvents.
CO2 neutral: reuses CO2
CO2 is affordable, environmentally friendly and reduces “strong” solvent use by up to 95%

Ultra Compact

Do more in less space with a smaller footprint than competing systems

Intuitive

PeakTrak® software removes the complexity of method development

Standard Features:

Flow rates from 50 to 200 mL/min for use of 2 and 3 cm columns
4 different cosolvent options with composition from 5 to 70% for elution of more polar compounds than other systems
Column oven with selection valve for up to six columns
Autoinjector to enable multiple injections of a single sample or stacked injection workflow
Choice of UV or UV-Vis PDA detectors standard

*ACCQPrep* SFC System**
Flow Rate Range	50-200 mL/min
Gradient Linearity	+/- 1%
System Co-Solvent Range	5-70%
System Backpressure Range	100-160 bar
Maximum System Operating Pressure	414 bar
Column Selector Valve	Standard; 6 columns (2 or 3 cm x 25 cm or less)
Column Oven (Temp range)	Standard (+5 °C above ambient to 70 °C)
CO₂ DELIVERY PUMP
CO₂ Inlet Pressure	55-140 bar (3-10 °C)
Flow Rate Range	20-200 g/min
CO-SOLVENT PUMP
Flow Rate Range	0.5-165 mL/min
Number of Co-Solvents	4 Co-Solvent Inlets
GLS Makeup Pump	Standard; Automated up to 5 mL/min
SAMPLE INTRODUCTION
Autoinjector	Standard 5 mL syringe, Allows multiple injections from a single vessel
Sample Injection	Modifier Stream Injection via Sample Loop (5 mL standard); other sizes may be installed and configured on the system
Stacked Injection Capability	Standard
DETECTOR
Detector Options	Variable UV PDA (200-400 nm) or Variable UV-VIs PDA (200-800 nm)
FRACTIONATION COLLECTION
Fractionation Valve	Standard; up to 8 user containers
Fraction Pooling Ability	Standard
Open Bed Fraction Collector	Optional with ACCQPrep SFC 2×2 or 4×2 AutoSampler
CONTROL SOFTWARE
Integrated Screen & Processor	15” High Res Touchscreen ; Internal CPU; Linux Redhat
Software	PeakTrak
Gradient Optimization	Standard; Focused Gradient Generator
Stacked Injection Wizard	Standard
Scale Up Wizard	Standard
Miscellaneous
Active Cosolvent and Waste Level Sensing	Standard
RFID Rack Sensing	Standard with ACCQPrep SFC 2×2 or 4×2 AutoSampler
SYSTEM DIMENSIONS
Component Dimensions (cm W x D x H)	Base ACCQPrep SFC: 41 x 56 x 73 SFC AS 2×2: 34 x 56 x 66 w/enclosure: 40 x 69 x 76 SFC AS 4×2: 58 x 56 x 66 w/enclosure: 64 x 69 x 76
Total System Benchtop Dimensions (cm W x D)	ACCQPrep SFC w/SFC AS 2×2 Enclosure: 81 x 69 ACCQPrep SFC w/SFC AS 4×2 Enclosure: 115 x 69

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